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methotrexate treatment

Joan i am taking both methotrexate and plaquenil but at one half the usual dose for each.

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methotrexate is bound in part to serum albumin after absorption, and toxicity may be increased because of displacement by certain drugs such as salicylates, sulphonamides, phenytoin, and some antibacterials such as tetracycline, chloramphenicol and para-aminobenzoic acid.

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therefore, patients receiving concomitant therapy with methotrexate and other potential hepatotoxins e.

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