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Heparins were administered in more than 90 of the patients and the relative rate of bleeding between clopidogrel and placebo was not significantly affected by the concomitant heparin therapy.

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taking other nsaids, corticosteroids, or blood thinners for example, clopidogrel plavix and generic or warfarin coumadin and generic can also increase the risk of bleeding.

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hmg-coa reductase inhibitors eg, simvastatin because the risk of side effects, such as muscle pain, weakness, and kidney problems, may be increased oral anticoagulants eg, warfarin because the risk of side effects, including the risk of bleeding, may be increased bexarotene or oral antidiabetic agents eg, glyburide, repaglinide, pioglitazone because their actions and the risk of their side effects may be increased by lopid sulfonylureas eg, glipizide because their effectiveness may be decreased by lopid.

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