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As with all antidepressants, paroxetine should be used with caution in patients with a history of mania.
Ssris and snris, including paroxetine, have been associated with cases of clinically significant hyponatremia in elderly patients, who may be at greater risk for this adverse event see precautions , hyponatremia .
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This means a 20 pound dog would take a single 10 mg paroxetine tablet each day.
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Both are in a class of drugs called selective serotonin reuptake inhibitors ssris , a class that also includes fluoxetine prozac , paroxetine paxil and sertraline zoloft .
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patients receiving doses of 40 and 60 mg paroxetine experienced a mean reduction of approximately 6 and 7 points, respectively, on the ybocs total score which was significantly greater than the approximate 4-point reduction at 20 mg and a 3-point reduction in the placebo-treated patients.