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Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine and does not inhibit monoamine oxidase or the reuptake of serotonin.
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the company was also fined for promoting wellbutrin bupropion approved at the time for major depressive disorder and also sold as a smoking-cessation aid, zyban for weight loss and the treatment of attention deficit hyperactivity disorder, sexual dysfunction and substance addiction.
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at least 14 days should elapse between discontinuation of an maoi and initiation of bupropion.
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the pharmacokinetics of bupropion and its active metabolites were not statistically significantly different in patients with mild to moderate cirrhosis when compared to healthy volunteers, although more variability was observed between individual patients.
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psychotherapy and, if necessary, antidepressant medication such as bupropion wellbutrin and generics , citalopram celexa and generics , and fluoxetine prozac and generics , can often help.
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