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A study by see et al estimated that 5156 emergency department ed visits for digoxin toxicity occurred annually in the united states between 2005 and 2010.
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bradycardia and heart block caused by digoxin are parasympathetically mediated and respond to atropine.
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30 however, comments on this study suggested that digoxin is not effective at reducing cancer risk at therapeutic concentrations of the drug, 31 so the results need further investigation.
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5,9,10 while digoxin s positive neurohormonal effects in hf patients may be attenuated or lost when beta-blockers are concomitantly prescribed, the association between digoxin and mortality observed in our study was independent of beta-blocker use.
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in cases where a large amount of digoxin has been ingested hyperkalaemia may be present due to release of potassium from skeletal muscle.
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