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Since uncorrected hyperkalemia may be fatal, serum potassium levels must be monitored at frequent intervals especially in patients first receiving dyazide hydrochlorothiazide and triamterene , when dosages are changed or with any illness that may influence renal function.
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the renal clearances of hydrochlorothiazide and the pharmacologically active metabolite of triamterene, the sulfate ester of hydroxytriamterene, have been shown to be reduced and the plasma levels increased following maxzide triamterene and hydrochlorothiazide administration to elderly patients and patients with impaired renal function.
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ace inhibitors , eg enalapril aliskiren angiotensin ii receptor antagonists , eg losartan ciclosporin drospirenone heparin non-steroidal anti-inflammatory drugs nsaids , eg indometacin, diclofenac, ibuprofen potassium-containing salt substitutes such as lo-salt potassium salts, eg potassium citrate for cystitis other potassium-sparing diuretics eg spironolactone, triamterene these should not usually be taken in combination with dyazide potassium supplements these should not usually be taken in combination with dyazide tacrolimus.
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triamterene-hctz is the fda-approved generic form of brand-name dyazide.
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there is no experience with the use of more than one triamterene and hydrochlorothiazide tablet 75 mg 50 mg daily or more than two triamterene and hydrochlorothiazide tablets 37.
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