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The serum half-life of cefixime in healthy subjects is independent of dosage form and averages 3 to 4 hours but may range up to 9 hours in some normal volunteers.

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in one in vitro study in pooled serum, salicylic acid apparently displaced cefixime from protein binding sites, resulting in more than a 50 increase in concentrations of free cefixime; this effect appeared to be concentration-dependent.

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, e-mycin , eryc , ery-tab , erythrocin , and pce , erythromycin topical commercially available as a t s , erycette , t-stat , gemifloxacin commercially available as factive , ofloxacin commercially known as ocuflox , floxin , telithromycin commercially available as ketek , lomefioxacin hydrochloride commercially available as maxaquin , minocycline hydrochloride commercially available as minocin , fosfomycin tromethamine commercially available as monurol , penicillin with potassium commercially available as penicillin vk , veetids , trimethoprim commercially available as primsol , ciprofloxacin hydrochloride commercially available as proquin xr , rifampin, isoniazid and pyrazinamide commercially available as rifater , cefditoren commercially available as spectracef , cefixime commercially available as suprax , tetracycline commercially available as achromycin v and sumycin , tobramycin commercially available as tobrex , rifaximin commercially available as xifaxan , azithromycin commercially available as zithromax , azithromycin suspension commercially available as zmax , linezolid commercially available as zyvox , benzoyl peroxide and clindamycin.

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cefixime trihydrate tablets and suspension, given orally, are about 40 to 50 absorbed whether administered with or without food; however, time to maximal absorption is increased approximately 0.


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