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Its mechanism of action appears to be different from that of most other antidepressant drugs, although bupropion does act on some of the same neurotransmitters and neurotransmission pathways.

Aplenzin bupropion hydrobromide 174 mg po qday initially equivalent to 150 mg bupropion hcl ; after 1 week, may increase to usual target dose of 348 mg day equivalent to 300 mg bupropion hcl .

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If patients are taking any medicines, check for interactions before prescribing bupropion.

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The risk of seizure can be reduced if the bupropion hydrochloride extended-release tablets xl dose not exceed 450 mg once daily and the titration rate is gradual.

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There has been a case reported of a teenager who experienced seizure induced by insufflation of bupropion.

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Because bupropion is the generic alternative for wellbutrin and zyban, there is no manufacturer-sponsored prescription assistance program for bupropion sr 150 mg.

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